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RECRUITING
NCT05960955
PHASE2

Cadonilimab Combination With Chemotherapy With or Without AK117 in Resectable Gastric or Gastroesophageal Junction Adenocarcinoma

Sponsor: Akeso

View on ClinicalTrials.gov

Summary

This trial is a Phase II study. All patients are resectable Gastric or Gastroesophageal Junction Adenocarcinoma, Eastern Cooperative Oncology Group (ECOG) performance status 0-1.The purpose of this study is to evaluate the efficacy and safety of cadonilimab combined with chemotherapy with or without AK117 neoadjuvantin treatment of resectable Gastric or Gastroesophageal Junction Adenocarcinoma.

Official title: Phase II Clinical Study of Cadonilimab Combination With Chemotherapy With or Without the Anti-CD47 Antibody AK117 Neoadjuvant/Adjuvant Therapy for Resectable Gastric or Gastroesophageal Junction Adenocarcinoma

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

90

Start Date

2023-11-13

Completion Date

2027-11-30

Last Updated

2023-11-18

Healthy Volunteers

No

Interventions

DRUG

Cadonilimab

IV infusion,Specified dose on specified days

DRUG

AK117

IV infusion,Specified dose on specified days

DRUG

Oxaliplatin

IV infusion,Specified dose on specified days

DRUG

Tegafur-gimeracil-oteracil potassium

Oral,Specified dose on specified days

DRUG

Docetaxel

IV infusion,Specified dose on specified days

DRUG

5-Fluorouracil

IV infusion,Specified dose on specified days

Locations (1)

Tianjin Provincial Tumor Hospital

Tianjin, China