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Eltrombopag for Peripheral Blood Stem Cell Harvest
Sponsor: National Taiwan University Hospital
Summary
The goal of this clinical trial is to explore the activity of eltrombopag in lymphoma patients receiving autologous hematopoietic stem cell harvest. The main questions it aims to answer are: * Determine the efficacy of adding eltrombopag during autologous hematopoietic stem cell mobilization and harvest. * Determine the pharmacokinetics and pharmacodynamics of serum eltrombopag concentration, circulating CD34+ cells during autologous hematopoietic stem cell mobilization. Participants will receiving additional eltrombopag during stem cell harvest procedure. The amount of harvested stem cells will be compared with historical group to see if eltrombopag could increase the amount of harvested stem cells.
Official title: Eltrombopag Plus G-CSF for Human CD34+ Cell Mobilization in Patients With Lymphoma Undergoing Autologous Stem Cell Harvest
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
46
Start Date
2023-08-15
Completion Date
2026-03-01
Last Updated
2024-10-18
Healthy Volunteers
No
Interventions
Eltrombopag olamine
Patients will receive eltrombopag 75 mg/day from ESHAP D6 until end of stem cell harvest.
Locations (1)
National Taiwan University Hospital
Taipei, Taiwan