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RECRUITING
NCT05961410
PHASE2

Eltrombopag for Peripheral Blood Stem Cell Harvest

Sponsor: National Taiwan University Hospital

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to explore the activity of eltrombopag in lymphoma patients receiving autologous hematopoietic stem cell harvest. The main questions it aims to answer are: * Determine the efficacy of adding eltrombopag during autologous hematopoietic stem cell mobilization and harvest. * Determine the pharmacokinetics and pharmacodynamics of serum eltrombopag concentration, circulating CD34+ cells during autologous hematopoietic stem cell mobilization. Participants will receiving additional eltrombopag during stem cell harvest procedure. The amount of harvested stem cells will be compared with historical group to see if eltrombopag could increase the amount of harvested stem cells.

Official title: Eltrombopag Plus G-CSF for Human CD34+ Cell Mobilization in Patients With Lymphoma Undergoing Autologous Stem Cell Harvest

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

46

Start Date

2023-08-15

Completion Date

2026-03-01

Last Updated

2024-10-18

Healthy Volunteers

No

Interventions

DRUG

Eltrombopag olamine

Patients will receive eltrombopag 75 mg/day from ESHAP D6 until end of stem cell harvest.

Locations (1)

National Taiwan University Hospital

Taipei, Taiwan