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Thromboxane Function in Women With Endometriosis
Sponsor: Penn State University
Summary
The goal of this clinical trial is to compare neurovascular regulation in women with endometriosis and healthy women. The main questions it aims to answer are: * Do women with endometriosis have greater blood pressure and pain responses to a stimulus than healthy women? * Do women with endometriosis have greater platelet activity than healthy women? Participants will take aspirin and/or placebo and will: * perform hand grip exercise and cold pressor tests * undergo iontophoresis and blood draw Researchers will compare women with and without endometriosis to see if there is a difference in neurovascular regulation.
Official title: The Role of Thomboxane A2 and it's Receptor in Vascular Regulation in Women With Endometriosis
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
96
Start Date
2024-01-01
Completion Date
2027-08-01
Last Updated
2025-05-04
Healthy Volunteers
Yes
Conditions
Interventions
Aspirin
650 mg aspirin (Acetylsalicylic acid)
Placebo
placebo capsule
Locations (1)
Noll Laboratory
University Park, Pennsylvania, United States