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RECRUITING
NCT05962034
PHASE4

Thromboxane Function in Women With Endometriosis

Sponsor: Penn State University

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to compare neurovascular regulation in women with endometriosis and healthy women. The main questions it aims to answer are: * Do women with endometriosis have greater blood pressure and pain responses to a stimulus than healthy women? * Do women with endometriosis have greater platelet activity than healthy women? Participants will take aspirin and/or placebo and will: * perform hand grip exercise and cold pressor tests * undergo iontophoresis and blood draw Researchers will compare women with and without endometriosis to see if there is a difference in neurovascular regulation.

Official title: The Role of Thomboxane A2 and it's Receptor in Vascular Regulation in Women With Endometriosis

Key Details

Gender

FEMALE

Age Range

18 Years - 45 Years

Study Type

INTERVENTIONAL

Enrollment

96

Start Date

2024-01-01

Completion Date

2027-08-01

Last Updated

2025-05-04

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

Aspirin

650 mg aspirin (Acetylsalicylic acid)

OTHER

Placebo

placebo capsule

Locations (1)

Noll Laboratory

University Park, Pennsylvania, United States