Clinical Research Directory

Inclusion Criteria: * Male or female subject over 19 years of age and written informed consent is obtained. * Subject who has bilaterally symmetrical of masseter at visual and palpable assessment. * Subject who average masseter muscle thickness of at least 14mm on each side in males and 12mm in females at maximum clenching by ultrasonography. * Subject who has a masseter muscle hypertrophy scale of 4(marked) or more as determined by investigator. * Subject who fully understands this clinical trial and voluntarily writes ICF in the clinical trial. Exclusion Criteria: * Subject who had previously received botulinum toxin within 12 weeks prior to the study entry. * Subject who got any facial aesthetic procedure (e.g. surgery, laser, thread treatment etc.) in masseter muscle area within 48 weeks prior to the study entry. * Subject who has a disease(e.g. Temporo mandibular joint disorder, etc.) * Subject who were diagnosed Myasthenia gravis, Lambert-Eaton syndrome, amyotrophic lateral sclerosis, or any other condition that might influence with neuromuscular function. * Subject who had taken medication(e.g. muscle relaxant, polypeptide antibiotics, aminoglycoside antibiotics, etc.) within 4 weeks prior to the study entry. * Subject who are hypersensitive to investigational drug components (botulinum toxin, serum albumin, etc.) * Subject who are pregnant or lactating or planing pregnancy or disagreed to avoid pregnancy during study period. * Subject who participate other clinical trials within 4 weeks prior to the study entry. * Subject who are not eligible for this study at the discretion of the investigator.