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Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars
Sponsor: University of Michigan
Summary
The purpose of this randomized, controlled clinical study is to evaluate if application of 38% SDF increases the efficacy of local anesthesia during operative dentistry on permanent molars affected by molar-incisor hypoplasia (MIH). The goal is to determine if pre-operative application of SDF results in improved local anesthesia and decrease in procedural pain in MIH affected teeth, thereby addressing an important challenge in routine clinical practice and contributing to the development of a treatment protocol for MIH affected molars.
Official title: Effect of Silver Diamine Fluoride on Local Anesthesia Efficacy in Molar Incisor Hypomineralization-affected Molars in Children: A Randomized Clinical Trial
Key Details
Gender
All
Age Range
6 Years - 11 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2023-06-12
Completion Date
2027-12-31
Last Updated
2026-02-12
Healthy Volunteers
Yes
Interventions
SDF
38% SDF will be applied to the hypoplastic area of the enrolled first permanent molar.
Placebo
An inert liquid will be applied to the hypoplastic area of the enrolled first permanent molar.
Locations (1)
University of Michigan
Ann Arbor, Michigan, United States