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ENROLLING BY INVITATION
NCT05964868
PHASE3

Efficacy of Liposomal Bupivacaine Post Septorhinoplasty

Sponsor: Jessyka Lighthall

View on ClinicalTrials.gov

Summary

The objective of this study is to determine if there is a difference in post-operative pain after septorhinoplasty when long-acting liposomal bupivacaine is used for local anesthesia compared to other standard local anesthetic regimens.

Official title: The Efficacy of Liposomal Bupivacaine in the Management of Post-operative Pain Following Septorhinoplasty: A Single-blinded, Prospective Clinical Trial

Key Details

Gender

All

Age Range

18 Years - 99 Years

Study Type

INTERVENTIONAL

Enrollment

72

Start Date

2024-02-05

Completion Date

2027-07

Last Updated

2026-04-03

Healthy Volunteers

Yes

Interventions

DRUG

Liposomal Bupivacaine

Patients will receive post-operative liposomal bupivacaine (EXPAREL®) at the surgical site at the completion of their septorhinoplasty.

DRUG

0.25% bupivacaine with 1:200,000 epinephrine

Non-liposomal encapsulated bupivacaine at the surgical site at the completion of septorhinoplasty.

OTHER

Placebo - Saline solution

This group will receive a one-time 5 mL injection of saline post-operatively at the surgical site.

Locations (1)

Jessyka Lighthall

Hershey, Pennsylvania, United States