Clinical Research Directory

Inclusion Criteria: * In order to be eligible to participate in this study, a subject must meet all of the following criteria: 1. Diagnosed with liver metastases of colorectal origin for which surgical resection is proposed and meet at least one of the following criteria: 1. Scheduled for surgical resection of \>3 CRLM or; 2. completed neo-adjuvant therapy, of which the last course was completed within 3 months before surgery or; 3. Scheduled for surgery because of a locally recurrent liver metastasis. 2. ≥18 years old. 3. Willing and capable to give informed consent before study specific procedures Exclusion Criteria: * A potential subject who meets any of the following criteria will be excluded from participation in this study: 1. Patients with contraindications for SGM-101 1. History of any anaphylactic shock; 2. Patients pregnant or breastfeeding (pregnancy should be ruled out by a pregnancy test within two weeks prior to administration of the conjugate); 3. Known positive test for human immunodeficiency virus (HIV), hepatitis B surface antigen (HBsAG) or hepatitis C virus (HCV) antibody or patients with untreated serious infections; 4. Previous administration of SGM-101 2. Patients with contraindications for Indocyanine green: 1. Allergy for shells and/or clamps 2. Hyperthyroidism 3. Known allergy for ICG 3. Any condition that the investigator considers to be potentially jeopardizing the patient's well-being or the study objectives