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Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF
Sponsor: University of California, San Francisco
Summary
The purpose of this study is to demonstrate the safety, efficacy, and feasibility of short-course post-operative antibiotic treatment for simple and complicated appendicitis
Official title: Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX) Using Desirability of Outcome Ranking (DOOR) and Response Adjusted for Duration of Antibiotic Risk (RADAR) -A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
145
Start Date
2023-06-06
Completion Date
2026-06-30
Last Updated
2025-05-08
Healthy Volunteers
No
Conditions
Interventions
Multiple standard of care antibiotics for appendicitis, at physicians' discretion
Standard of Care Antibiotic use will be restricted to none or up to 24 hours of post-operative antibiotics.
Multiple standard of care antibiotics for appendicitis, at physicians' discretion
Standard of Care Antibiotic use will be permitted for 24 hours or up to 4 days of post-operative antibiotics.
Locations (1)
Zuckerberg San Francisco General Hospital
San Francisco, California, United States