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RECRUITING
NCT05966675
NA

Physiologic Cardiac Pacing to Prevent Left Ventricular Dysfunction Post TAVI

Sponsor: Medical University of Silesia

View on ClinicalTrials.gov

Summary

The study aims to compare permanent Conduction System Pacing (CSP) with the standard therapy - Right Ventricular Pacing (RVP) or Biventricular Pacing (BVP) - in preventing the development and progression of symptomatic Chronic Heart Failure (CHF) and improving survival in patients after Transcatheter Aortic Valve Implantation (TAVI).

Official title: Physiologic Cardiac Pacing to Prevent Left Ventricular Dysfunction Post Transcatheter Aortic Valve Implantation

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

500

Start Date

2024-02-27

Completion Date

2028-06

Last Updated

2025-06-08

Healthy Volunteers

No

Interventions

DEVICE

conduction system pacing

Implantation of cardiac implantable electronic device (CIED) with conduction system pacing (left bundle branch area pacing or his bundle pacing).

DEVICE

right ventricular or biventricular pacing

Implantation of cardiac implantable electronic device with right ventricular or biventricular pacing according to left ventricular ejection fraction and current ESC guidelines.

Locations (1)

Medical University of Silesia in Katowice

Katowice, Poland