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RECRUITING
NCT05968885
PHASE4

Evaluation the Efficacy Between Botox Injection and Combination Pharmacotherapy in Patients With Detrusor Overactivity

Sponsor: Mackay Memorial Hospital

View on ClinicalTrials.gov

Summary

To investigates the effects of botulinum toxin type A bladder injection compared to combined pharmacotherapy with Mirabegron and Solifenacin.

Official title: Evaluation of the Efficacy and Urodynamic Outcomes Between Intradetrusor onabotulinumtoxinA Injection and Combination Pharmacotherapy in Patients With Detrusor Overactivity

Key Details

Gender

FEMALE

Age Range

20 Years - 90 Years

Study Type

INTERVENTIONAL

Enrollment

300

Start Date

2021-10-01

Completion Date

2026-12-31

Last Updated

2025-05-09

Healthy Volunteers

No

Interventions

PROCEDURE

Intradetrusor Botox® (onabotulinumtoxinA) injection

The toxin produced by Clostridium botulinum binds to the nerves endings and inhibits the muscular contractions, help to treat overactivity of the bladder muscles.

DRUG

Combine Mirabegron and Solifenacin.

Combination pharmacotherapy

Locations (1)

Mackay Memorial Hospital

Taipei, Taiwan