Clinical Research Directory

Inclusion Criteria: 1. Provision of signed and dated informed consent form 2. Male or female, aged 65-89 years 3. Closed fracture of the proximal femur including the anatomic areas of femoral neck, intertrochanteric and subtrochanteric region 4. Patient indicated for surgical treatment (surgical fixation or arthroplasty) as per orthopaedic surgeon 5. Ability to take oral medication and be willing to adhere to the study drug regimen and to the nutritional guidance provided by nutritional experts. Exclusion Criteria: 1. Patients with open fractures 2. Surgical treatment other than surgical fixation or arthroplasty, such as proximal femur resection 3. Known allergic reactions to components of the study drugs or who do not tolerate oral nutritional supplementation (e.g. total parenteral nutrition or food allergies) 4. Decisional impairment 5. Prisoners