Clinical Research Directory

Inclusion Criteria: * Adult with a diagnosis of PD by a movement disorders neurologist * Previous placement, at least six months, of bilateral Medtronic Precept DBS as standard of care treatment for their PD. * Stable and clinically optimized DBS parameters for three months prior to enrollment. * Demonstrate the ability to safely mount and dismount a recumbent exercise cycle with an upright back. * Willingness to withhold antiparkinsonian medication and DBS stimulation. * Exercise clearance using the American College of Sports Medicine (ACSM) Pre-participation Health Screen: a. If the ACSM screen recommends medical clearance, the subject must obtain medical clearance by their health care provider prior to participation; b. Those who choose not to obtain physician clearance will not be eligible for participation. Exclusion Criteria: * Diagnosis of dementia or any neurocognitive impairment that compromises the ability to provide informed consent. * A musculoskeletal issue that limits one's ability to cycle * Neurological disease other than Parkinson's disease (i.e. multiple sclerosis, stroke) that impacts motor or cognitive function * Uncontrolled cardiovascular risk factor such as a current cardiac arrhythmia, uncontrolled hypertension, untreated deep vein thrombosis, etc.