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Long-term Use of CCB and Breast Cancer Risk
Sponsor: Curtin University
Summary
The goal of this retrospective observational study is to examine whether long-term calcium channel blocker (CCB) use is associated with the development of breast cancer amongst women enrolled in three longitudinal cohort studies in Australia and the Netherlands . The main questions it aims to answer are: * Is long-term CCB use associated with the development of breast cancer amongst women enrolled in three longitudinal cohort studies in Australia and the Netherlands and what is the dose-response nature of this association. * Does differences in the association between calcium channel blocker use and the development of breast cancer exist between Australian and Dutch women. The investigators will utilise data from the Australian Longitudinal Study on Women's Health (ALSWH) , 45 and Up Study and Rotterdam study.
Official title: Association of Long-term Use of Calcium Channel Blockers (CCB) and Risk of Breast Cancer: A Retrospective Longitudinal Observational Study
Key Details
Gender
FEMALE
Age Range
45 Years - Any
Study Type
OBSERVATIONAL
Enrollment
68500
Start Date
2022-07-01
Completion Date
2025-12
Last Updated
2024-08-21
Healthy Volunteers
Not specified
Conditions
Interventions
Calcium channel blocker
Drugs with ATC code C08 will be categorised as calcium channel blockers.
Beta blocker
Drugs with ATC code C07 will be categorised as beta-blockers.
Diuretic
Drugs with ATC code C03 will be categorised as diuretics.
RAS
Drugs with ATC code C09 will be categorised as RAS (agents acting on the renin angiotensin system).
Other AHT
Drugs with ATC code C02 will be categorised as other antihypertensives.
None AHT
None AHT
Locations (1)
Curtin university
Bentley, Western Australia, Australia