Clinical Research Directory

Inclusion Criteria: * Patient ≥ 18 years * Presence of a structural heart disease and an implantable cardioverter defibrillator (ICD) * Documented sustained monomorphic VT that requires ICD intervention (e.g., shock or anti-tachycardia stimulation) * The VT is inducible by ICD via non-invasive programmed stimulation (NIPS) or during electrophysiology measurement * Patient must have failed or become intolerant to at least one antiarrhythmic medication * Patient must have failed at least one invasive catheter ablation procedure, or have a contraindication to a catheter ablation procedure, or have VT thought to arise from a protected location * Ability to give a written informed consent and willingness to return for follow-up Exclusion Criteria: * Pregnancy or breastfeeding * Lack of evidence of a myocardial scar triggering the VT * Polymorphic VT or ventricular fibrillation (VF) as a clinical heart rhythm * Advanced symptomatic heart failure defined as NYHA Class IV heart failure * Previous radiotherapy with cardiac involvement * Life expectancy \< 6 months, in the absence of VT, as best based on clinical judgment by the treating and enrolling physicians * Any condition that is deemed a contraindication in the judgment of the investigators