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RECRUITING
NCT05976347
PHASE4

Identifying and Treating Depression in the Orthopaedic Trauma Population

Sponsor: Wake Forest University Health Sciences

View on ClinicalTrials.gov

Summary

The goal of this trial is to pilot a way for orthopaedic surgeons to safely screen for depression and provide treatment for depression with medication. The main questions it aims to answer are: 1. What are the outcomes of patients who screen positive for depressive symptoms and are prescribed either an Selective serotonin reuptake inhibitors (SSRI) or serotonin and norepinephrine reuptake inhibitors (SNRI). 2. What are the outcomes of patients who screen positive for depressive symptoms and choose not to pursue treatment with medication?

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2025-06-25

Completion Date

2026-05

Last Updated

2026-04-08

Healthy Volunteers

No

Conditions

Interventions

DRUG

Fluoxetine 20 MG

Fluoxetine 20 mg once daily

DRUG

Duloxetine 30 MG

Duloxetine 30 mg once daily

OTHER

Observation

Referral to behavioral health and resources for addressing depressive symptoms

Locations (1)

Wake Forest University Health Sciences

Winston-Salem, North Carolina, United States