Clinical Research Directory

Inclusion Criteria: * Between 20 and 70 years of age * First-ever clinical manifest stroke * Right or left hemiparesis * Scores higher than 7 and lower than 45 on the Fugl-Meyer scale. * Expected will undergo spinal cord stimulation surgery. * Able to comply with procedures and follow up. * Stable medical condition without cardiopulmonary disease or dysautonomia that would contraindicate participation in upper extremity rehabilitation or testing activities. Exclusion Criteria: * Pregnancy or breast feeding. * Have Major depressive disorder. * Had a mental illness within one year or been treated in the past. * Have significant cognitive impairment (MMSE\<24) or serious disease that could affect the ability to participate in study activities. * Cardiovascular or musculoskeletal disease or injury that would prevent full participation in physical therapy intervention. * Receiving anticoagulant, anti-spasticity or anti-epileptic medications prior to or throughout the duration of the study. * Unable to read and/or comprehend the consent form. * Have concerns about this trial and do not sign consent. * Presence of joint contractures deemed by study clinician/investigator to be too severe to participate in study activities.