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COMPLETED
NCT05982392
PHASE2/PHASE3

Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative Pain

Sponsor: Dow University of Health Sciences

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to compare in Tramadol, Naproxen sodium and Placebo in participants presenting with irreversible pulpitis in their mandibular molar teeth. The main question\[s\] it aims to answer are: * Local anesthetic efficacy and . * Postoperative pain. Participants will receive premedication treatments 60 minutes prior to the local anesthesia administration. Researchers will compare Tramadol, Naproxen sodium and Placebo to evaluate their effects on Inferior alveolar nerve block efficacy and Postoperative pain.

Official title: Effect of Preoperative Tramadol and Naproxen Sodium on Efficacy of Local Anesthesia and Post-operative Pain in Patients With Symptomatic Irreversible Pulpitis

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

139

Start Date

2023-03-01

Completion Date

2023-08-15

Last Updated

2026-06-25

Healthy Volunteers

Yes

Interventions

DRUG

Tramadol

Tramadol 100mg will be given 60 minutes before start of procedure.

DRUG

Naproxen Sodium

Naproxen sodium 550mg will be given 60 minutes before start of procedure.

DRUG

Placebo

Placebo will be given 60 minutes before start of procedure.

Locations (1)

Dow International Dental College

Karachi, Sindh, Pakistan