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Effect of CYP2C9*3 Polymorphism on Ibuprofen in Pakistani Population
Sponsor: Riphah International University
Summary
The goal of the study was to identify the effect of CYP2C9 gene polymorphism in the Pakistani population. The main question it aims to answer were: * to evaluate the effect of this genetic polymorphism on the clinical efficacy of Ibuprofen * to evaluate the effect of this genetic polymorphism on the clinical tolerability of Ibuprofen Participants were prescribed Ibuprofen after molar tooth extraction.
Official title: Effect of CYP2C9*3 rs 1057910 Polymorphism on the Efficacy and Tolerability of Ibuprofen After Molar Tooth Extraction in Pakistani Population
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2022-11-01
Completion Date
2023-07-31
Last Updated
2026-06-02
Healthy Volunteers
No
Conditions
Interventions
Ibuprofen 400 mg
Ibuprofen 400 mg TDS
Placebo
Placebo tablet
Locations (1)
Ammarah Amjad
Rawalpindi, Punjab Province, Pakistan