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NOT YET RECRUITING
NCT05987007
NA

Sleep Interventions and Neurocognitive Outcomes

Sponsor: New York State Psychiatric Institute

View on ClinicalTrials.gov

Summary

This protocol focuses on the effect of sleep interventions on improving sleep and building cognitive/brain resilience in older adults with amnestic mild cognitive impairment and sleep disturbance. Two sleep interventions, cognitive behavioral therapy for insomnia (CBTI) and acoustic slow-wave activity enhancement (SWAE), will be utilized in a pilot randomized clinical trial in which participants are randomized to different treatment groups (CBTI or SWAE). Participants will be assessed over a 6-month period in order to examine the impact of sleep treatments on neuropsychological outcomes and cognitively mediated everyday functioning.

Official title: Sleep Interventions and Neurocognitive Outcomes in Amnestic Mild Cognitive Impairment

Key Details

Gender

All

Age Range

60 Years - 85 Years

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2026-05-01

Completion Date

2028-12-31

Last Updated

2026-04-06

Healthy Volunteers

No

Interventions

DEVICE

Acoustic slow-wave activity enhancement

The acoustic enhancement of slow-wave activity will be conducted using the Dreem2 headband. This device utilizes five dry-EEG electrodes (O1, O2, FpZ, F7, and F8), a 3D accelerometer, and a pulse oximeter to detect slow-wave activity and generates acoustic stimulation of slow-waves to augment slow-wave sleep.

BEHAVIORAL

Cognitive behavioral therapy for insomnia

Cognitive behavioral therapy for insomnia (CBTI) is a well-established first-line or complimentary treatment for insomnia which consists of cognitive and behavioral modifications, including addressing maladaptive sleep-related behaviors, controlling sleep environment, and limiting time spent in bed.

Locations (1)

New York State Psychiatric Institute

New York, New York, United States