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IMPACT TRIAL: Efficacy and Safety of Pemvidutide in Subjects With Nonalcoholic Steatohepatitis (NASH)
Sponsor: Altimmune, Inc.
Summary
Purpose of this study is to assess the effects of pemvidutide on NASH resolution and NASH fibrosis.
Official title: A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Pemvidutide in Non-Cirrhotic Subjects With Nonalcoholic Steatohepatitis (NASH)
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
212
Start Date
2023-07-27
Completion Date
2025-11-25
Last Updated
2026-05-18
Healthy Volunteers
No
Conditions
Interventions
Pemvidutide
Administered once weekly by subcutaneous injection
Placebo
Administered once weekly by subcutaneous injection
Locations (40)
Altimmune Clinical Study Site
Chandler, Arizona, United States
Altimmune Clinical Study Site
Peoria, Arizona, United States
Altimmune Clinical Study Site
Tucson, Arizona, United States
Altimmune Clinial Study Site
Tucson, Arizona, United States
Altimmune Clinical Study Site
North Hollywood, California, United States
Altimmune Clinical Study Site
Panorama City, California, United States
Altimmune Clinical Study Site
Englewood, Colorado, United States
Altimmune Clinical Study Site
Bradenton, Florida, United States
Altimmune Clinical Study Site
Fort Myers, Florida, United States
Altimmune Clinical Study Site
Hialeah Gardens, Florida, United States
Altimmune Clinical Study Site
Miami Lakes, Florida, United States
Altimmune Clinical Study Site
Port Orange, Florida, United States
Altimmune Clinical Study Site
Sarasota, Florida, United States
Altimmune Clinical Study Site
West Palm Beach, Florida, United States
Altimmune Clinical Study Site
Dalton, Georgia, United States
Altimmune Clinical Study Site
Marietta, Georgia, United States
Altimmune Clinical Study Site
Bastrop, Louisiana, United States
Altimmune Clinical Study Site
Shreveport, Louisiana, United States
Altimmune Clinical Study Site
Clarksville, Tennessee, United States
Altimmune Clinical Study Site
Germantown, Tennessee, United States
Altimmune Clinical Study Site
Austin, Texas, United States
Altimmune Clinical Study Site
Bellaire, Texas, United States
Altimmune Clinical Study Site
Edinburg, Texas, United States
Altimmune Clinical Study Site
Edinburg, Texas, United States
Altimmune Clinical Study Site
Georgetown, Texas, United States
Altimmune Clinical Study Site
Houston, Texas, United States
Altimmune Clinical Study Site
San Antonio, Texas, United States
Altimmune Clinical Study Site
San Antonio, Texas, United States
Altimmune Clinical Study Site
West Jordan, Utah, United States
Royal Prince Alfred Hospital
Camperdown, New South Wales, Australia
Liverpool Hospital
Liverpool, New South Wales, Australia
Princess Alexandra Hospital/ Translational Research Institute
Woolloongabba, Queensland, Australia
Flinders Medical Centre
Bedford Park, South Australia, Australia
St. Vincent's Hospital Melbourne
Fitzroy, Victoria, Australia
Austin Health
Heidelberg, Victoria, Australia
Box Hill Hospital
Box Hill, Victory, Australia
Monash Hospital
Clayton, Victory, Australia
Fiona Stanley Hospital
Murdoch, Western Australia, Australia
Sir Charles Gairdner Hospital
Nedlands, Western Australia, Australia
Altimmune Clinical Study Site
San Juan, Puerto Rico