Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
COMPLETED
NCT05990686
PHASE4

Paracetamol Plus Tramadol Versus Fentanyl in Day Case Surgeries

Sponsor: Zagazig University

View on ClinicalTrials.gov

Summary

Postoperative pain is an important problem, especially for day case surgeries. It has negative effects on patient's hemodynamics and can cause delayed ambulation resulting in prolonged duration of hospital stay and poor patient satisfaction. Multiple analgesic strategies have been proposed including NSAID, opioids, epidural analgesia. Each of them has its limitations. In this study the investigators will compare the effect of preemptive use of paracetamol plus tramadol versus preemptive intravenous fentanyl in controlling postoperative pain

Official title: Paracetamol Plus Tramadol Versus Fentanyl as Pre-emptive Analgesia for Enhanced Recovery After Day-Case Surgeries: A Randomised Controlled Trial

Key Details

Gender

All

Age Range

21 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

102

Start Date

2025-06-01

Completion Date

2025-12-31

Last Updated

2026-09-15

Healthy Volunteers

Yes

Interventions

DRUG

tramadol plus paracetamol

Patients in Group T received an intravenous infusion of paracetamol (15 mg/kg) with tramadol (1 mg/kg), completed immediately before induction of anaesthesia.

DRUG

Fentanyl Injection

Group F received a single intravenous injection of fentanyl 1.5 µg/kg before induction.

Locations (1)

Zagazig University , Fuculty of Medicine

Zagazig, Sharquia, Egypt