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Sevoflurane General Anesthetic and Spatial Memory in Humans
Sponsor: University of Chile
Summary
The goal of this observational study is to learn about the effect of general anesthetic on spatial memory in adults who will undergo to an elective surgery. The main question it aims to answer is: • A surgical event under general anesthesia with sevoflurane transiently impairs spatial memory in humans and induces an increase in inflammatory cytokines. Participants will perform a virtual maze test and plasma samples will be taken before and after surgery.
Official title: Study of the Effect of Sevoflurane General Anesthetic on Spatial Memory in Humans
Key Details
Gender
All
Age Range
30 Years - 50 Years
Study Type
OBSERVATIONAL
Enrollment
22
Start Date
2023-08-14
Completion Date
2025-12-30
Last Updated
2025-11-20
Healthy Volunteers
Not specified
Conditions
Interventions
Surgery/general anesthesia
Adult patients between the ages of 30 and 50 who are to undergo elective surgery under general anesthesia will have their spatial memory tested and interleukin 1beta and alpha tumor necrosis measured before and after surgery.
Locations (2)
Centro de Investigación Cínica Avanzada (CICA), Hospital Clinico de la Universidad de Chile
Santiago, RM, Chile
Hospital Clinico de la Universidad de Chile
Santiago, RM, Chile