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Electroencephalographic Biomarker to Predict Postoperative Delirium
Sponsor: University of Chile
Summary
Acute post-operatory cognitive dysfunction states are one of the most important complications in older patients that underwent surgery. Among them postoperative delirium (POD) is the the most studied. Patients who develop delirium have poorer long-term outcomes, such as longer length of hospital stay, institutionalization at discharge, and even higher mortality, and consequently, the human and economic costs significantly increase for the health system. Here the research team will use an observational cohort, investigator blinded in five-center with a primary endpoint to validate intraoperative EEG analysis as a reliable biomarker of postoperative delirium.
Official title: Electroencephalographic Biomarker to Predict the Development of Postoperative Delirium: a Protocol of an Observational Study in a Cohort of Patients From Five Centers
Key Details
Gender
All
Age Range
60 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
264
Start Date
2023-09-01
Completion Date
2026-06-30
Last Updated
2025-11-20
Healthy Volunteers
Yes
Conditions
Interventions
POD risk estimation using PEUMA
A software will analyze intraoperative EEG recording for the estimation of a POD Risk Index
Locations (2)
Hospital Clinico Universidad de Chile
Santiago, Santiago Metropolitan, Chile
Instituto Nacional del Cancer
Santiago, Santiago Metropolitan, Chile