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NCT05992506

Electroencephalographic Biomarker to Predict Postoperative Delirium

Sponsor: University of Chile

View on ClinicalTrials.gov

Summary

Acute post-operatory cognitive dysfunction states are one of the most important complications in older patients that underwent surgery. Among them postoperative delirium (POD) is the the most studied. Patients who develop delirium have poorer long-term outcomes, such as longer length of hospital stay, institutionalization at discharge, and even higher mortality, and consequently, the human and economic costs significantly increase for the health system. Here the research team will use an observational cohort, investigator blinded in five-center with a primary endpoint to validate intraoperative EEG analysis as a reliable biomarker of postoperative delirium.

Official title: Electroencephalographic Biomarker to Predict the Development of Postoperative Delirium: a Protocol of an Observational Study in a Cohort of Patients From Five Centers

Key Details

Gender

All

Age Range

60 Years - 100 Years

Study Type

OBSERVATIONAL

Enrollment

264

Start Date

2023-09-01

Completion Date

2026-06-30

Last Updated

2025-11-20

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

POD risk estimation using PEUMA

A software will analyze intraoperative EEG recording for the estimation of a POD Risk Index

Locations (2)

Hospital Clinico Universidad de Chile

Santiago, Santiago Metropolitan, Chile

Instituto Nacional del Cancer

Santiago, Santiago Metropolitan, Chile