Clinical Research Directory

Inclusion Criteria: * Employed healthcare workers aged 18 years and older. * Have availability and interest in participating in a 1 year study. * Ability to comply with basic instructions and be able to sit still, comfortably during sessions. * Experiencing symptoms of stress meeting threshold score on the Perceived Stress Scale (PSS ≥ 14). Exclusion Criteria: * No internet access, as some visits collected electronically * Unable, unwilling, or incompetent to provide informed consent. * Physically unable to come to the study visits, or to sit still, comfortably in a chair for up to 1 hour. * Severe hearing impairment (because the subject will be using ear buds during CR). * Weight is over the chair limit (400 pounds). * Currently enrolled in another active intervention research study. * Prior use of: HIRREM, HIRREM-SOP, Brainwave Optimization (BWO), Cereset, Cereset Research, Cereset Home, or a wearable configuration of the same (B2, or B2v2). * Prior use of the following modalities within one month before enrollment: electroconvulsive therapy (ECT), prior use of transcranial magnetic stimulation (TMS), transcranial direct current stimulation (TDCS), alpha stimulation, eye movement desensitization and reprocessing (EMDR), brain spotting, neurofeedback, biofeedback, or deep brain stimulation (DBS). * Known seizure disorder. * Thoughts of active suicide within the last 3 months. * Current medical student.