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Moderately Hypofractionated Adaptive Radiotherapy for Cervical Cancer
Sponsor: Peking Union Medical College Hospital
Summary
External radiation given in 25 fractions or so together with weekly chemotherapy and followed by 5 or 6 fractions of brachytherapy is the standard of care for patients with locally advanced cervical cancer. We hope to develop external moderately hypofractionated radiotherapy of cervical cancer based on adaptive radiotherapy.The objective of this study is to evaluate the efficacy and treatment-related toxicity of moderately hypofractionated adaptive radiotherapy in the treatment of cervical cancer.
Official title: Clinical Research of Moderately Hypofractionated Radiotherapy for Cervical Cancer
Key Details
Gender
FEMALE
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2023-09-19
Completion Date
2025-12-31
Last Updated
2025-06-08
Healthy Volunteers
Yes
Interventions
Moderately hypofractionated adaptive radiotherapy (ART)+ High-dose rate (HDR) Brachytherapy
Experimental: 43.35Gy/17F external beam radiotherapy (EBRT) with adaptive radiotherapy (ART) + HDR-Brachytherapy Drug: Concurrent Chemotherapy Weekly cisplatin 40 mg/m2
Locations (1)
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China