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Changes in Inhibition and Valuation After Eating
Sponsor: Icahn School of Medicine at Mount Sinai
Summary
An impaired ability to exert control has been implicated in bulimia nervosa (BN), but this impairment may not represent a stable trait or be the most effective focus for treatment. This project aims to understand how predictions and value-based decisions about control may be abnormally influenced by eating in individuals with BN, thereby maintaining cycles of binge eating, purging, and restriction.
Official title: Dynamic Neural Computations Underlying Cognitive Control in Bulimia Nervosa
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2023-12-12
Completion Date
2027-12-31
Last Updated
2026-02-17
Healthy Volunteers
Yes
Conditions
Interventions
Fasting state
16 hours of fasting
Fed state
Fed a standardized meal
Magnetic Resonance Imaging
Neuroimaging with computational modeling
Locations (1)
Center of Excellence in Eating and Weight Disorders at the Icahn School of Medicine at Mount Sinai
New York, New York, United States