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Prospective Cohort of Single-dose Radiotherapy for Painful Bone Lesions in Multiple Myeloma
Sponsor: Instituto do Cancer do Estado de São Paulo
Summary
Multiple myeloma is a plasma cell neoplasm that can cause painful bone lesions. The main treatment for these lesions and pain control is radiotherapy, usually in daily fractions. In 2017, a phase III study proved the effectiveness of using a single dose of 8 Gy, but without description of several important oncological outcomes. This is a single-arm prospective cohort study. This study aims to describe these outcomes, including retreatment rate and bone events. Also, as secondary objectives, describe the quality of life and use of analgesic medications in this population.
Official title: Prospective Cohort Assessing the Impact of Single-dose Radiotherapy in the Treatment of Painful Bone Lesions in Patients With Multiple Myeloma
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2023-07-31
Completion Date
2029-07-31
Last Updated
2023-08-18
Healthy Volunteers
No
Conditions
Interventions
Single-dose involved-site radiotherapy
Single-dose of 8 Gy at involved-site radiotherapy
Locations (1)
University of Sao Paulo
São Paulo, São Paulo, Brazil