Clinical Research Directory
Browse clinical research sites, groups, and studies.
CEST in Low-grade Glioma Study
Sponsor: Sunnybrook Health Sciences Centre
Summary
Low grade gliomas (LGGs) are malignant, infiltrative and incurable brain tumours that typically present in the younger population. This project proposes to use non-contrast metabolic "Saturation Transfer" (ST)-MRI to evaluate LGG tumour progression and aims to predict early changes in LGG. Early identification of LGG patients whose tumours will progress will permit early interventions. ST-MRI does not involve any intravenous injection of contrast and which acquires metabolic information not seen by standard MRI.
Official title: A Multi-institutional Observational Study of CEST Imaging in Low-grade Glioma
Key Details
Gender
All
Age Range
12 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2022-08-12
Completion Date
2028-08-12
Last Updated
2023-08-18
Healthy Volunteers
No
Conditions
Interventions
Saturation Transfer (ST)-MRI
Non-contrast magnetic resonance imaging "Saturation Transfer" scans consisting of magnetization transfer (MT) and chemical exchange saturation transfer (CEST)
Locations (2)
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
St. Michael's Hospital
Toronto, Ontario, Canada