Clinical Research Directory

Inclusion Criteria: Subjects will include those men and women: * aged 65-80 years, * with amnestic Mild Cognitive Impairment (Montreal Cognitive Assessment Battery score \[MoCA\] total score 19-25 or a phonemic fluency score of =\<12 (with MoCA \>25) or semantic fluency score of =\<15 (with MoCA \>15); and score of \> 1.0 on the Mail-in Cognitive Function Screening Instrument), * obese (body mass index 27.5-40 kg/m\^2), * sedentary, and * willing to participate in all aspects of the proposed intervention. Exclusion Criteria: Reasons for participant exclusion will include: * secondary causes of obesity, * evidence of clinical dementia (MoCA score \< 18), severe chronic kidney disease (eGFR \<45 ml/min/1.73m\^2), * heart failure, * high grade arrhythmias, * severe valvular heart disease, * severe asthma or chronic obstructive lung disease, * diabetes requiring insulin, * musculoskeletal or neurologic problems that would preclude participation in aerobic exercise training, * a major psychiatric disorder, * a history of drug abuse, * alcohol consumption \>14 drinks/week, * gastric bypass surgery, * non-English speaking, or * a life-limiting comorbid medical condition (e.g. cancer).