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Amulet™ ADVANCE LAA
Sponsor: Abbott Medical Devices
Summary
This is a prospective, multicenter, observational study intended to characterize real-world outcomes on the commercially available Amulet device in the United States. Over 600 subjects have been enrolled at 16 US clinical sites. Subjects will be followed through 24 months in accordance with each site's standard care practices.
Official title: A Real-World Study to Observe Outcomes of Patients Undergoing Closure With the Amplatzer™ Amulet™ Left Atrial Appendage Occluder
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
610
Start Date
2023-07-12
Completion Date
2027-06
Last Updated
2025-10-01
Healthy Volunteers
No
Conditions
Interventions
Left atrial appendage occlusion (LAAO)
Implantation of an Amplatzer Amulet left atrial appendage occluder
Locations (16)
Arizona Arrhythmia Research
Phoenix, Arizona, United States
Arkansas Heart Hospital
Little Rock, Arkansas, United States
Baptist Medical Center
Jacksonville, Florida, United States
Usman R. Siddiqui, MD
Winter Park, Florida, United States
PERC - O'Fallon
O'Fallon, Illinois, United States
Kansas City Cardiac Arrhythmia Research Foundation
Overland Park, Kansas, United States
Cardiovascular Research Institute of Kansas
Wichita, Kansas, United States
Providence Hospital
Southfield, Michigan, United States
Bryan Heart
Lincoln, Nebraska, United States
CHI Health Creighton University Medical Center-Bergan Mercy
Omaha, Nebraska, United States
New York University Hospital
New York, New York, United States
Pinnacle Health System
Mechanicsburg, Pennsylvania, United States
Trident Medical Center
Charleston, South Carolina, United States
Vanderbilt Heart & Vascular Institute
Nashville, Tennessee, United States
Baylor All Saints Medical Center at Fort Worth
Fort Worth, Texas, United States
Heart Rhythm Associates
Shenandoah, Texas, United States