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Personalized Optimization of Systematic Prostate Biopsy
Sponsor: Fujian Medical University Union Hospital
Summary
Targeted biopsy combined systematic biopsy is the gold standard for diagnosis of prostate cancer. Excessive cores in systematic biopsy increases the risk of puncture trauma， bleeding and infection. On the basis of establishing a model with DRS stratification to reduce the cores of systematic biopsy, we propose the (12 cores -x) model innovatively. We hope that through this prospective study to verify the efficacy of the model and provide patients with a new biopsy model with high accuracy and fewer complications. In this study， patients with suspected prostate cancer were randomly divided into two groups. Experimental group received targeted biopsy combined personalized systematic biopsy, and the control group received systematic biopsy .The differences of the detection rate of Prostate cancer between the two groups were compared.
Official title: Diagnostic Performance of a Individualized Reduced-Core Biopsy Strategy in Prostate Cancer: A Prospective, Randomized Controlled Study
Key Details
Gender
MALE
Age Range
50 Years - 95 Years
Study Type
INTERVENTIONAL
Enrollment
330
Start Date
2023-08-23
Completion Date
2025-12-30
Last Updated
2025-12-18
Healthy Volunteers
No
Conditions
Interventions
Personalized Optimization of Systematic Prostate Biopsy
Login the model based on our previous study (https://daringsky.shinyapps.io/prediction\_v2/) allows for input of age, BMI, serum PSA, size and location of suspicious lesions, PIRADS - V2 score, and prostate volume to generate an individualized needle distribution map,then targeted biopsy combined personalized optimization of systematic prostate biopsy was performed.
Locations (1)
Department of Urology, Fujian Union Hospital, Fujian Medical University
Fuzhou, Fujian, China