Clinical Research Directory

Inclusion criteria IBS patients * A diagnosis of IBS according to Rome IV criteria, as follows: * Recurrent abdominal pain, on average, at least 1 day per week in the last 3 months, associated with 2 or more of the following criteria: * Related to defecation; * Associated with a change in stool frequency; oAssociated with a change in stool form (appearance). * Criteria fulfilled for the last 3 months with symptom onset at least 6 months prior to diagnosis. * Minimal baseline score of 150 points on the IBS-SSS scale * Age between 18 and 80 years; * Ability to understand and speak the Dutch language * Ability to understand how to utilize the ESM and Traqq applications. Inclusion criteria IBD patients * Patients with IBD diagnosed in accordance with current ECCO guidelines, with IBD- IBS and with chronic abdominal pain, as follows: * MIAH score \<3 and/or * Fecal calprotectin \< 150 ug/g or negative IUS or colonoscopy and * Fulfilling the Rome IV criteria for IBS. * Age between 18 and 80 years; * Minimal baseline score of 150 points on the IBS-SSS scale * Ability to understand and speak the Dutch language * Ability to understand how to utilize the ESM and Traqq applications. Exclusion criteria IBS patients * Any organic explanation for the abdominal symptoms; * A history of abdominal surgery, except for uncomplicated appendectomy, laparoscopic cholecystectomy and hysterectomy is present; * Pregnant or lactating at the baseline visit. Exclusion criteria IBD patients * Uncertainty about the absence of active inflammation * Uncertainty about other explanatory causes for the GI symptoms, such as bile acid malabsorption, intestinal stenosis, or small intestinal bacterial overgrowth; * Pregnant or lactating at the baseline visit.