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ACTIVE NOT RECRUITING
NCT06002204

Studying the Health of Asians to Advance Knowledge, Treatments, and Interventions for Depression

Sponsor: University of Texas Southwestern Medical Center

View on ClinicalTrials.gov

Summary

SHAKTI (from the Sanskrit word for "power") is a 5-year natural history, longitudinal, prospective study of a cohort of 6,000 participants that will help uncover the socio-demographic, lifestyle, clinical, psychological, and neurobiological factors that contribute to antidepressant treatment response (remission, recurrence, relapse and individual outcomes in depressive disorders) and resilience. As this is an exploratory study, we will assess a comprehensive panel of carefully selected participant specific parameters - socio-demographic (age, sex, gender, race, ethnicity, economic); life habits (physical activity, substance use); clinical (medical history, anxious depression, early life trauma), biological (biomarkers in blood, saliva, urine, stool), behavioral (cognitive, emotional), neurophysiological (EEG), and neuroimaging (magnetic resonance imaging; MRI) with the goal of developing the most robust predictive models of depression treatment response and of outcomes.

Official title: Studying the Health of Asians to Advance Knowledge, Treatments, and Interventions for Depression (SHAKTI)

Key Details

Gender

All

Age Range

10 Years - Any

Study Type

OBSERVATIONAL

Enrollment

6000

Start Date

2024-03-01

Completion Date

2035-02

Last Updated

2025-08-21

Healthy Volunteers

Yes

Interventions

OTHER

Observational Study

No Treatment or Intervention Provided

Locations (1)

UT Southwestern Medical Center

Dallas, Texas, United States