Clinical Research Directory

Inclusion Criteria: * Pregnant women with a singleton pregnancy between 24 weeks and 0 days and 31 weeks and 6 days with severe, early-onset fetal growth restriction, admitted in hospital or frequently evaluated ambulatory by CTG (according to local protocol) for fetal monitoring. * Fetal growth restriction is defined in line with the international Delphi consensus as biometric ultrasound measurement of the abdominal circumference (AC) OR a combination of measurements resulting in an estimated fetal weight (EFW) below the 3rd percentile (\<p3) OR a combination of EFW \<p10 AND uterine artery pulsatility index (PI) \>p95 OR umbilical artery Doppler PI \>p95. * Maternal age ≥ 18 years. * Able to provide written informed consent for collection and use of data on informed consent form in available language. Exclusion Criteria: * Known congenital or chromosomal anomalies influencing perinatal outcome. * Imminent labour or expected maternal indication for delivery \< 48 hours.