Clinical Research Directory
Browse clinical research sites, groups, and studies.
Insulin Resistance in Egyptian Patients With Multiple Sclerosis
Sponsor: Assiut University
Summary
The goal of this three-phase interventional study is to determine the prevalence of Insulin resistance in non-diabetic patients with multiple sclerosis in Egypt The main questions it aims to answer are: 1. what is the prevalence of insult resistance among Egyptian patients with Multiple sclerosis? 2. what are the effects of insulin resistance on multiple sclerosis disease activity and progression 3. what are the effects of treating insulin resistance on multiple sclerosis disease activity and progression participants with MS will be tested for IR to determine its prevalence, in the 2nd phase a group of MS patients with IR will be compared with another control group of MS patients without IR for clinical, laboratory, and radiological markers of disease activity and progression twice at baseline and after 1 year. in the 3rd phase, patients with IR will be divided into 2 groups one who will receive appropriate treatment for IR and the other group without treatment of IR and will be compared by the end of the 2nd year for clinical, laboratory and radiological markers of disease activity and progression
Official title: Insulin Resistance in Non-diabetic Multiple Sclerosis Patients: Prevalence, Pre and Post-treatment Effect on Clinical, Cognitive Profile, Laboratory, and Radiological Markers
Key Details
Gender
All
Age Range
18 Years - 50 Years
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2024-12
Completion Date
2027-06
Last Updated
2024-07-30
Healthy Volunteers
Not specified
Conditions
Interventions
treatment of insulin resistance with appropriate modality according to each patient
insulin resistance will be treated with either diet alone or combined diet and appropriate pharmacological treatment with the net result of normalization of HOMA IR index