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Effect of Eszopiclone on Adherence to CPAP and Severity of Insomnia in Patients With COMISA
Sponsor: University of Sao Paulo General Hospital
Summary
The comorbidity between obstructive sleep apnea (OSA) and insomnia (COMISA) is common, and associated with poorer sleep quality. CPAP adherence among COMISA patients is worst than among those with OSA only. The investigators will compare the effect of Eszopiclone 3mg or placebo for 14 days on adherence to CPAP after 30 days and after 6 months.
Official title: Effect of Eszopiclone on Adherence to Continuous Positive Airway Pressure (CPAP) and Severity of Insomnia in Patients With Comorbidity Between Insomnia and Obstructive Sleep Apnea (COMISA)
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2023-08-24
Completion Date
2026-03-20
Last Updated
2026-05-29
Healthy Volunteers
Yes
Conditions
Interventions
Eszopiclone 3 mg
Patients starting CPAP treatment will be randomized to either Eszopiclone or Placebo arm
Placebo
Patients starting CPAP treatment will be randomized to either Eszopiclone or Placebo arm
Locations (1)
Sleep Laboratory, Heart Institute, Pulmonary Division, Hospital das Clínicas da Universidade de São Paulo
São Paulo, Brazil