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COMPLETED
NCT06018038

Arm Exercise Capacity and Maximal Oxygen Consumption With Breast Cancer

Sponsor: Hacettepe University

View on ClinicalTrials.gov

Summary

Breast cancer is the most common type of cancer among women worldwide. The incidence rate has reached approximately 16%. According to 2016 data from the Ministry of Health, the incidence of breast cancer in Turkey is 46.8 per 100,000 people and approximately 17,000 women are diagnosed with breast cancer each year. While breast cancer survival rate is 80% in developed countries, this rate varies between 40-60% in low-middle income countries. Survival can be increased with early diagnosis and more effective treatment methods. However, a wide range of treatment-related complications are observed during and/or after breast cancer treatment. Cancer survivors are exposed to a variety of direct (local/regional therapy, systemic therapy and supportive care) and indirect factors (modifiable and non-modifiable risk factors) that can have adverse effects on pulmonary, cardiovascular, hematologic and musculoskeletal components. Oxygen consumption in cancer patients may be adversely affected by aging, deconditioning, existing comorbidities, cancer pathophysiology and cancer treatments (surgery, radiation, chemotherapy and hormone therapy). Although decreased functional capacity is common after breast cancer treatment, there are few studies evaluating maximal arm exercise capacity with oxygen consumption.

Official title: Arm Function in Breast Cancer Survivors: Is There a Decrease in Maximal Capacity and Oxygen Utilization?

Key Details

Gender

FEMALE

Age Range

15 Years - 65 Years

Study Type

OBSERVATIONAL

Enrollment

60

Start Date

2024-06-01

Completion Date

2024-12-01

Last Updated

2026-05-19

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

Arm Exercise Capacity, Peak Oxygen Consumption (VO2peak)

peak arm exercise capacity

DIAGNOSTIC_TEST

Muscle oxygenation

Muscle oxygenation (SmO2 ) was recorded using a device (Moxy, Fortiori Design LLC, Minnesota, USA) that measures local SmO2 in muscle capillaries using near-infrared spectroscopy (NIRS)

Locations (1)

Hacettepe University

Ankara, State, Turkey (Türkiye)