Clinical Research Directory

Inclusion Criteria: * Age 8-18 * Patient at TSRH * Diagnosis of lumbosacral spina bifida (myelomeningocele, meningocele, lipoma of spinal cord, myelocystocele, diastematomyelia, fatty/thickened filum) * Incontinence refractory to compliant catheterization (compliance with catheterization as assessed by their treating provider) * Patient able and willing to undergo urodynamic testing without sedation * No surgical reconstruction with the exception of a single appendicovesicostomy (APV) * No Botox treatments within 1 year of enrollment * Patient willing and able to stop bladder medications (anticholinergics or beta agonists) 2 weeks prior to pre-intervention bladder diary, questionnaires and UDS * Patient lives close enough to TSRH and CMC to be willing to return for UDS, teaching, and clinic visits as detailed above * Patient/family speak English Exclusion Criteria: * Ages \<8 or \>18 * Diagnosis not listed above * Patients that have received reconstructive surgeries (i.e. augmentation or bladder neck sling) with the exception for a single APV * Patient received Botox treatment within 1 year of enrollment * Patient unable or unwilling to stop bladder medications (anticholinergics or beta agonists) * Patients with high-risk bladders, as assessed by their treating provider (i.e. poorly compliant bladders with high end-fill pressures) * Non-English speaking * Patients who are pregnant * Patients who are suspected of being pregnant * Patients who are nursing