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ACTIVE NOT RECRUITING
NCT06026644

Health-Related Quality of Life Outcomes in Patients With Aggressive B-Cell Lymphomas Treated With CAR-T Cell Therapy in Real Life

Sponsor: Gruppo Italiano Malattie EMatologiche dell'Adulto

View on ClinicalTrials.gov

Summary

This study will ultimately aim at providing the scientific community with patient-reported health status data that will contribute facilitate decision-makings. Short- and long-term HRQoL and symptoms will be evaluated in a longitudinal fashion over time to improve the understanding of the impact of the disease and CAR-T cell therapy on patients-wellbeing, symptom burden and daily functioning. This study will capture useful information on the impact of treatment toxicity, the burden of procedures on HRQoL outcomes. The planned collection of PRO and physician-reported adverse events ad early time point will help to compare and integrate these two points of view in healthcare assessment.

Official title: Health-Related Quality of Life Outcomes in Patients With Aggressive B-Cell Lymphomas Treated With CAR-T Cell Therapy in Real Life: A Multicenter Prospective Observational Study

Key Details

Gender

All

Age Range

18 Years - 99 Years

Study Type

OBSERVATIONAL

Enrollment

170

Start Date

2022-06-29

Completion Date

2026-04-15

Last Updated

2024-07-25

Healthy Volunteers

No

Locations (13)

Aou Di Bologna - Policlinico S. Orsola-malpighi - Uoc Ematologia

Bologna, Italy

Asst Degli Spedali Civili Di Brescia - Ssvd Centro Trapianti Midollo Per Adulti - Cattedra Di Ematologia

Brescia, Italy

AOU Careggi - SOD terapie cellulari e Medicina Trasfusionale

Florence, Italy

Irccs Aou San Martino - Genova - Uo Ematologia E Trapianti

Genova, Italy

Fondazione Irccs "Istituto Nazionale Tumori" - Milano - Sc Ematologia

Milan, Italy

Ao Ospedali Riuniti Villa Sofia Cervello - Palermo - Uo Ematologia Ad Indirizzo Oncologico

Palermo, Italy

Asl Pescara, Presidio Ospedaliero 'Spirito Santo' - Uoc Ematologia Clinica

Pescara, Italy

Aou Pisana - Uo Ematologia Universitaria

Pisa, Italy

Aou Policlinico Umberto I - Dipartimento Di Medicina Traslazionale - Sezione Ematologia

Roma, Italy

Ististuto Clinico Humanitas - Rozzano - Uo Oncologia Medica Ed Ematologia

Rozzano, Italy

Aou Città Della Salute E Della Scienza, Ospedale S. Giovanni Battista Molinette - Torino - Sc Ematologia - Università Degli Studi Di Torino

Torino, Italy

Aou Città Della Salute E Della Scienza, Ospedale S. Giovanni Battista Molinette - Torino - Sc Ematologia 2

Torino, Italy

Aulss 8 Berica - Ospedale Di Vicenza - Uoc Ematologia

Vicenza, Italy