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ACTIVE NOT RECRUITING
NCT06028009
NA

PRP Injections for Genitourinary Syndrome of Menopause

Sponsor: Medstar Health Research Institute

View on ClinicalTrials.gov

Summary

Platelet-rich plasma (PRP) is autologous blood which has been centrifuged to separate the supernatant resulting in a solution with high concentration of platelets. Injection of PRP stimulates cell growth and can has been proven safe and effective for uses in orthopedics, dermatology, and gynecology. Despite the relative paucity of data, the use of PRP as a therapy for sexual dysfunction and genitourinary symptoms in the setting of menopause has been patented as the O-Shot and V-Shot. This is a single-blinded randomized control trial to determine if PRP injections into the anterior vaginal wall improve sexual functioning in women diagnosed with the genitourinary syndrome of menopause (GSM) characterized by vaginal dryness/irritation.

Official title: Vaginal Injection of Platelet Rich Plasma (PRP) for the Genitourinary Syndrome of Menopause (GSM)

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2024-03-01

Completion Date

2026-04-30

Last Updated

2025-11-14

Healthy Volunteers

No

Interventions

PROCEDURE

Injection of platelet-rich plasma

Injection of autologous platelet-rich plasma into anterior vaginal wall

PROCEDURE

Injection of saline

Injection of sterile normal saline into anterior vaginal wall

Locations (1)

MedStar Lafayette Medical Centre

Washington D.C., District of Columbia, United States