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PRP Injections for Genitourinary Syndrome of Menopause
Sponsor: Medstar Health Research Institute
Summary
Platelet-rich plasma (PRP) is autologous blood which has been centrifuged to separate the supernatant resulting in a solution with high concentration of platelets. Injection of PRP stimulates cell growth and can has been proven safe and effective for uses in orthopedics, dermatology, and gynecology. Despite the relative paucity of data, the use of PRP as a therapy for sexual dysfunction and genitourinary symptoms in the setting of menopause has been patented as the O-Shot and V-Shot. This is a single-blinded randomized control trial to determine if PRP injections into the anterior vaginal wall improve sexual functioning in women diagnosed with the genitourinary syndrome of menopause (GSM) characterized by vaginal dryness/irritation.
Official title: Vaginal Injection of Platelet Rich Plasma (PRP) for the Genitourinary Syndrome of Menopause (GSM)
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2024-03-01
Completion Date
2026-04-30
Last Updated
2025-11-14
Healthy Volunteers
No
Conditions
Interventions
Injection of platelet-rich plasma
Injection of autologous platelet-rich plasma into anterior vaginal wall
Injection of saline
Injection of sterile normal saline into anterior vaginal wall
Locations (1)
MedStar Lafayette Medical Centre
Washington D.C., District of Columbia, United States