Clinical Research Directory

Inclusion Criteria: * nitial inclusion criteria: 1. Age 18-75 years old, regardless of gender; 2. ECOG PS score 0-1 points (Attachment 3.4); 3. Preoperative clinical staging for patients with suspected NSCLC lesions in Phase I (according to AJCC Eighth Edition staging standards, Attachment 3.5); 4. Thin slice CT indicates that the maximum tumor diameter is ≤ 2.0cm; 5. Pre operative CT prompts 0.5\<CTR\<1.0; 6. Good lung function (FEV1\>1.5 L or FEV1% ≥ 60%), able to tolerate both segmental resection and lobectomy; 7. The number of pulmonary nodules that need to be processed is ≤ 3, and the nodules are located in the same side of the lung; 8. Those who voluntarily sign the research informed consent form can comply with the research visit plan and other protocol requirements. Exclusion Criteria: Initial exclusion criteria: 1. Hypertension and diabetes difficult to control; 2. Pregnant or lactating women; 3. Those who have received anti-tumor treatment (radiotherapy, chemotherapy, Targeted therapy, immunotherapy) before surgery; 4. Previous history of lung surgery; 5. Interstitial pneumonia, Pulmonary fibrosis or severe Emphysema; 6. Those who undergo thoracotomy or change the surgical plan due to various reasons during surgery; 7. Severe mental illness; 8. Individuals with a history of severe heart disease, heart failure, myocardial infarction, or angina within the past 6 months; 9. Active bacterial or fungal infections that are difficult to control; 10. Individuals who have conducted other clinical trials in the three months prior to enrollment. Secondary exclusion criteria: 1. The postoperative pathological result was Benign tumor; 2. Postoperative pathological results of non NSCLC malignant tumors; 3. Non small cell lung cancer confirmed histologically during operation, but with malignant Pleural effusion and pleural dissemination