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Validation of the Clinical and Antimicrobial Effectiveness of a Clorexidine and Sodium DNA Based Mouthwash in Patients With Stage III and IV Periodontitis
Sponsor: University of Catania
Summary
Sodium DNA has several properties that may be beneficial in the management of bacterial biofilm in periodontitis. The aim of this RCT study is to clinically evaluate the antimicrobial and oral biofilm control properties of two mouthwashes containing Chlorhexidine 0.2% + Sodium DNA and Chlorhexidine 0.2% at two weeks, compared with a placebo, on patients with stage III or IV periodontitis.
Official title: Validation of the Clinical and Antimicrobial Effectiveness of a Clorexidine and Sodium DNA Based Mouthwash in Patients With Stage III and IV Periodontitis: a Randomized-controlled Clinical Trial
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
66
Start Date
2020-01-24
Completion Date
2024-04-20
Last Updated
2026-08-11
Healthy Volunteers
Yes
Conditions
Interventions
Non-surgical periodontal treatment
Subgingival biofilm ultrasonic debridement
Locations (1)
AOU Policlinico G. Rodolico
Catania, Italy, Italy