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Power Versus Temperature Controlled Ablation for Treatment of VT
Sponsor: University Hospitals Coventry and Warwickshire NHS Trust
Summary
Ventricular Tachycardia (VT) is a life threatening heart rhythm that comes from the bottom chambers of the heart (the ventricles) and is a leading cause of sudden cardiac death. The majority of patients that are at risk of VT or suffer a cardiac arrest will have an Internal Cardiac Defibrillator (ICD) in situ to treat the abnormal heart rhythm. The ICD can deliver a painful shock to restore normal heart rhythm but importantly does not treat the underlying cause. Current treatment for the prevention of recurrent VT include catheter ablation (CA) or medication. Long-term results with global 12 month VT-free survival rates with CA are around 50%. The trial is to compare 2 different types of ablation catheter that are used to cauterise small areas of unhealthy tissue within the heart that are responsible for VT: Diamond Temp (DT) and Tacticath/Tactiflex (TF). Our hypothesis is that the DT ablation catheter will provide comparable efficacy and safety for the treatment of VT as the current industry gold standard (TF).
Official title: A Randomised Control Trial of Power Versus Temperature-controlled Irrigated Radiofrequency Ablation for the Treatment of Ventricular Tachycardia (VT)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
64
Start Date
2022-09-26
Completion Date
2026-03-01
Last Updated
2024-09-19
Healthy Volunteers
No
Conditions
Interventions
Temperature controlled DiamondTemp (DT) ablation catheter
The DiamondTemp catheter is a new ablation catheter that uses 6 industrial grade diamonds to actually measure the temperature of the surface tissue being cauterised. This enables the DiamondTemp catheter to control the amount of power being delivered from the ablation catheter into the tissue being ablated by maintaining a constant temperature at the surface of the heart.
Tacticath/Tactiflex (TF) ablation catheter
The Tactiflex ablation catheter is currently the market leader and routinely used for VT ablation.
Locations (2)
University Hospital Coventry and Warwickshire NHS Trust
Coventry, West Midlands, United Kingdom
University Hospitals Sussex NHS Foundation Trust
Brighton, United Kingdom