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RECRUITING
NCT06028919
NA

Power Versus Temperature Controlled Ablation for Treatment of VT

Sponsor: University Hospitals Coventry and Warwickshire NHS Trust

View on ClinicalTrials.gov

Summary

Ventricular Tachycardia (VT) is a life threatening heart rhythm that comes from the bottom chambers of the heart (the ventricles) and is a leading cause of sudden cardiac death. The majority of patients that are at risk of VT or suffer a cardiac arrest will have an Internal Cardiac Defibrillator (ICD) in situ to treat the abnormal heart rhythm. The ICD can deliver a painful shock to restore normal heart rhythm but importantly does not treat the underlying cause. Current treatment for the prevention of recurrent VT include catheter ablation (CA) or medication. Long-term results with global 12 month VT-free survival rates with CA are around 50%. The trial is to compare 2 different types of ablation catheter that are used to cauterise small areas of unhealthy tissue within the heart that are responsible for VT: Diamond Temp (DT) and Tacticath/Tactiflex (TF). Our hypothesis is that the DT ablation catheter will provide comparable efficacy and safety for the treatment of VT as the current industry gold standard (TF).

Official title: A Randomised Control Trial of Power Versus Temperature-controlled Irrigated Radiofrequency Ablation for the Treatment of Ventricular Tachycardia (VT)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

64

Start Date

2022-09-26

Completion Date

2026-03-01

Last Updated

2024-09-19

Healthy Volunteers

No

Interventions

DEVICE

Temperature controlled DiamondTemp (DT) ablation catheter

The DiamondTemp catheter is a new ablation catheter that uses 6 industrial grade diamonds to actually measure the temperature of the surface tissue being cauterised. This enables the DiamondTemp catheter to control the amount of power being delivered from the ablation catheter into the tissue being ablated by maintaining a constant temperature at the surface of the heart.

DEVICE

Tacticath/Tactiflex (TF) ablation catheter

The Tactiflex ablation catheter is currently the market leader and routinely used for VT ablation.

Locations (2)

University Hospital Coventry and Warwickshire NHS Trust

Coventry, West Midlands, United Kingdom

University Hospitals Sussex NHS Foundation Trust

Brighton, United Kingdom