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WMT for Autism Spectrum Disorder (ASD)
Sponsor: The Second Hospital of Nanjing Medical University
Summary
Autism Spectrum Disorder (ASD) is a group of serious neurodevelopmental disorders. A significant comorbidity exists between ADHD and ASD: 30%-50% of individuals with ASD exhibit ADHD symptoms, and two-thirds with ADHD show ASD traits. Intestinal microbial disturbance is common in children with ASD. A great deal of evidence shows that intestinal microbes can influence the brain to play its role through "gut-brain-microbiota axis". We intend to explore the role of Washed Microbiota Transplantation in improving symptoms of children in ASD with or without ADHD; To study the potential etiological mechanism of WMT for the neurodevelopmental disorders.
Official title: Washed Microbiota Transplantation (WMT) for Autism Spectrum Disorder (ASD)
Key Details
Gender
All
Age Range
3 Years - 17 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2023-09-20
Completion Date
2027-05-01
Last Updated
2025-09-05
Healthy Volunteers
No
Conditions
Interventions
Washed Microbiota Transplantation
The prepared microbiota suspension was infused into the participates' lower gut.
Locations (2)
Department of Microbiota Medicine & Medical Centre for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China
SIR RUN RUN hospital of Nanjing Medical University
Nanjing, Jiangsu, China