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RECRUITING
NCT06033807

Active Screening of Latent Tuberculosis Infection in School Contacts of Active Tuberculosis Patients

Sponsor: Huashan Hospital

View on ClinicalTrials.gov

Summary

The goal of this observational study is to investigate the proportion of Mycobacterium tuberculosis (MTB) infection in school contacts of active tuberculosis (ATB) patients. The main questions it aims to answer are: * the proportion of MTB infection among school contacts of ATB patients * risk factors related to tuberculosis (TB) infection * health economic evaluation of screening strategy

Key Details

Gender

All

Age Range

13 Years - Any

Study Type

OBSERVATIONAL

Enrollment

31440

Start Date

2023-09-01

Completion Date

2025-12-31

Last Updated

2025-04-01

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

QuantiFERON-TB Gold (QFT) test

Participants will be tested by QuantiFERON-TB Gold (QFT) test to see if they have ever infected by MTB. Those with positive results will proceed to sputum Xpert MTB/RIF, physical examination and chest CT scan, as well as sputum culture if necessary to distinguish latent TB infection (LTBI) from ATB. X-ray scan is conditional on age above 15 years with a positive QuantiFERON-TB Gold (QFT) test result.

Locations (44)

Xinpu New Area Center of Disease Control

Zunyi, Guiyang, China

Dafang Center for Disease Control and Prevention

Bijie, Guizhou, China

Qixingguan Center for Disease Control and Prevention

Bijie, Guizhou, China

Nayong Center for Disease Control and Prevention

Bijie, Guizhou, China

Hezhang Center for Disease Control

Bijie, Guizhou, China

Jinsha Center for Disease Control

Bijie, Guizhou, China

Qianxi Center of Disease Control

Bijie, Guizhou, China

Weining Center of Disease Control

Bijie, Guizhou, China

Zhijin Center of Disease Control

Bijie, Guizhou, China

Liping Center for Disease Control and Prevention

Linping, Guizhou, China

Liuzhi Special District Center of Disease Control

Liupanshui, Guizhou, China

Panzhou Center of Disease Control

Liupanshui, Guizhou, China

Shuicheng District Center of Disease Control

Liupanshui, Guizhou, China

Cengong Center of Disease Control

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

Congjiang Ceter of Disease Control

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

Danzhai Center of Disease Control

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

Huangping Center of Disease Control

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

Jianhe Center of Disease Control

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

Jinping Center of Disease Control

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

Kaili Center of Disease Control

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

Leishan Center of Disease Control

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

Majiang Center of Disease Control

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

Rongjiang Center of Disease Control

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

Sansui Center of Disease Control

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

Shibing Center of Disease Control

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

Taijiang Center of Disease Control

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

Tianzhu Center of Disease Control

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

Zhenyuan Center of Disease Control

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

Qingzhen Center for Disease Control and Prevention

Qingzhen, Guizhou, China

Bozhou District Center of Disease Control

Zunyi, Guizhou, China

Chishui Center of Disease Control

Zunyi, Guizhou, China

Daozhen Center of Disease Control

Zunyi, Guizhou, China

Fenggang Center of Disease Control

Zunyi, Guizhou, China

Honghuagang District Center of Disease Control

Zunyi, Guizhou, China

Huichuan District Center of Disease Control

Zunyi, Guizhou, China

Meitan Center of Disease Control

Zunyi, Guizhou, China

Renhuai Center of Disease Control

Zunyi, Guizhou, China

Suiyang Center of Disease Control

Zunyi, Guizhou, China

Tongzi Center of Disease Control

Zunyi, Guizhou, China

Wuchuan Center of Disease Control

Zunyi, Guizhou, China

Xishui Center of Disease Control

Zunyi, Guizhou, China

Yuqing Center of Disease Control

Zunyi, Guizhou, China

Zhengan Center of Disease Control

Zunyi, Guizhou, China

Dalian Public Health Clinical Center

Dalian, Liaoning, China