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COMPLETED
NCT06034925
PHASE4

Maribavir vs. Valganciclovir for CMV Prophylaxis in High-Risk Kidney Transplant Recipients

Sponsor: Medical University of South Carolina

View on ClinicalTrials.gov

Summary

The purpose of this study is to find out if there is a difference in how well the standard MUSC cytomegalovirus (CMV) prevention medicine works, compared to a different medicine, in preventing CMV infections in kidney transplant recipients who are at risk for this type of infection, while also assessing the tolerability of these two regimens. The two medication regimens being compared are Valganciclovir (FDA approved to prevent and treat CMV infection) vs Maribavir (FDA approved to treat CMV infection) plus Acyclovir (FDA approved to prevent HSV infection).

Official title: Randomized Controlled Trial Comparing the Tolerability and Efficacy of Maribavir vs. Valganciclovir for CMV Prophylaxis in High-Risk Kidney Transplant Recipients

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

70

Start Date

2023-11-06

Completion Date

2025-08-30

Last Updated

2026-04-30

Healthy Volunteers

No

Interventions

DRUG

Maribavir

maribavir 400mg twice daily

DRUG

Valganciclovir

valganciclovir 900mg once daily

Locations (1)

Medical University of South Carolina

Charleston, South Carolina, United States