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RECRUITING
NCT06036446
NA

LATe Cerclage in High-risk Pregnancies (LATCH)

Sponsor: Thomas Jefferson University

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to determine whether cervical cerclage reduces the risk of preterm birth in patients with a short transvaginal ultrasound (TVU) cervical length (CL) ≤25mm between 24 0/7-26 6/7 weeks.

Official title: Cervical Cerclage for Short Cervix at 24-26 Weeks of Gestation: a Randomized Controlled Trial

Key Details

Gender

FEMALE

Age Range

18 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

329

Start Date

2023-11-10

Completion Date

2029-02

Last Updated

2025-04-16

Healthy Volunteers

Yes

Conditions

Interventions

PROCEDURE

Cervical cerclage

Transvaginal cervical cerclage placed between 24 0/7 - 26 6/7 weeks of gestation.

DRUG

Vaginal Suppository Progesterone

Continuing or initiation of vaginal progesterone 200mg daily until 36 weeks of gestation.

Locations (1)

Thomas Jefferson University

Philadelphia, Pennsylvania, United States