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Relation Between NAFLD and BM DENSITY
Sponsor: Assiut University
Summary
In general NAFLD is a common denominal for a broad spectrum of damage to the liver, which can be due to hepatocyte injury, inflammatory processes and fibrosis. This is normally seen on liver biopsy and can range from milder forms (steatosis) to the more severe forms (non-alcoholic steatohepatitis (NASH), advanced fibrosis, cirrhosis and liver failure). In these patients, advanced fibrosis is the major predictor of morbidity and liver-related mortality, and an accurate diagnosis of NASH and NAFLD is mandatory . NAFLD is closely associated with metabolic disorders, including central obesity, dyslipidaemia, hypertension, hyperglycaemia and persistent abnormalities of liver function tests. NAFLD was shown to be connected with diseases that are usually not dependent on obesity, such as sarcopenia and osteoporosis Target of the study : 1. Clarify predictive value of fibroscan and u/s in diagnosis of NAFLD. 2. Estimate the metabolic effect of NAFLD on bone density 3. Estimate the correlation between obesity , NAFLD and BMD
Official title: Relation Between Non- Alcoholic Fatty Liver Disease and Bone Mineral Density in Egyptian Adults
Key Details
Gender
All
Age Range
18 Years - 50 Years
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2023-10-01
Completion Date
2026-12-01
Last Updated
2023-09-15
Healthy Volunteers
Not specified
Conditions
Interventions
Fibroscan
Fibroscan is device to detect degree of liver fibrosis in NAFLD patients Dexa scan device detect degree of osteoporosis in NAFLD patients