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Leukocyte-rich PRP or Leukocyte-free PRP vs Placebo in the Treatment of Epicondylitis
Sponsor: Istituto Ortopedico Rizzoli
Summary
The EPIC-PRP study is a double-blind randomized controlled clinical trial with 1:1:1 allocation.The objective of the study is to evaluate by means of a randomized controlled, double-blind clinical trial the clinical outcomes of echo-guided injection of PRP with or without leukocytes compared with echo-guided injection of saline for minimally invasive treatment of patients with epicondylitis resistant to conservative therapy. It will be the aim of the study to evaluate the efficacy and safety of the injection procedures by revealing the improvement and incidence of adverse events following treatment
Official title: Leukocyte-rich PRP or Leukocyte-free PRP vs Placebo in the Treatment of Epicondylitis: a Randomized Controlled Clinical Trial
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
240
Start Date
2023-03-23
Completion Date
2027-03
Last Updated
2025-09-29
Healthy Volunteers
No
Conditions
Interventions
Injection of autologous leukocyte rich platelet rich plasma (LR-PRP)
Patients will be treated with a single eco-guided injection of Autologous LR-PRP in the elbow affected by epicondylitis.
Injection of autologous leukocyte poor platelet rich plasma (LP-PRP)
Patients will be treated with a single eco-guided injection of Autologous LP-PRP in the elbow affected by epicondylitis.
Placebo (saline solution)
Patients will be treated with a single injections of saline solution in the elbow affected by epicondylitis.
Locations (1)
Istituto Ortopedico Rizzoli
Bologna, Italy