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COMPLETED
NCT06040905
NA
Causal Effect of Coenzyme Q10 Nutrition and Cognitive Dysfunction in the Metabolic Storm (Hyperglycemia and Sarcopenia) and Brain-derived Neurotrophic Factor
Sponsor: Chung Shan Medical University
View on ClinicalTrials.gov
Summary
The aim of the study is to investigate the effects of coenzyme Q10 supplementation (150 mg twice daily; 300 mg/day for 12 weeks) on coenzyme Q10 status, glucose parameters, BDNF, myokines, and cognitive function in patients with mild cognitive impairment (MCI) or Alzheimer's disease (AD) and hyperglycemia, either without sarcopenia risk or with pre-sarcopenia/sarcopenia risk.
Key Details
Gender
All
Age Range
50 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
51
Start Date
2024-01-24
Completion Date
2026-02-12
Last Updated
2026-08-21
Healthy Volunteers
No
Interventions
DIETARY_SUPPLEMENT
Coenzyme Q10
300 mg/day (150 mg/b.i.d)
OTHER
Placebo
Starch
Locations (1)
Chung Shan Medical University Hospital
Taichung, Taiwan