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RECRUITING
NCT06040905
NA

Causal Effect of Coenzyme Q10 Nutrition and Cognitive Dysfunction in the Metabolic Storm (Hyperglycemia and Sarcopenia) and Brain-derived Neurotrophic Factor

Sponsor: Chung Shan Medical University

View on ClinicalTrials.gov

Summary

The aim of the study is to investigate the effect of coenzyme Q10 supplementation (150 mg/b.i.d, 300 mg/d, 12 weeks) on coenzyme Q10, glucose parameters, BDNF, myokines, and cognitive function in mild cognitive impairment (MCI) and Alzheimer's disease (AD) patients who combined with hyperglycemia but without sarcopenia, or with hyperglycemia and pre-sarcopenia.

Key Details

Gender

All

Age Range

50 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2023-12-26

Completion Date

2026-07-31

Last Updated

2024-02-07

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

Coenzyme Q10

300 mg/day (150mg/b.i.d)

OTHER

Placebo

Starch, dextrin

Locations (1)

Chung Shan Medical University Hospital

Taichung, Taiwan