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COMPLETED
NCT06040905
NA

Causal Effect of Coenzyme Q10 Nutrition and Cognitive Dysfunction in the Metabolic Storm (Hyperglycemia and Sarcopenia) and Brain-derived Neurotrophic Factor

Sponsor: Chung Shan Medical University

View on ClinicalTrials.gov

Summary

The aim of the study is to investigate the effects of coenzyme Q10 supplementation (150 mg twice daily; 300 mg/day for 12 weeks) on coenzyme Q10 status, glucose parameters, BDNF, myokines, and cognitive function in patients with mild cognitive impairment (MCI) or Alzheimer's disease (AD) and hyperglycemia, either without sarcopenia risk or with pre-sarcopenia/sarcopenia risk.

Key Details

Gender

All

Age Range

50 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

51

Start Date

2024-01-24

Completion Date

2026-02-12

Last Updated

2026-08-21

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

Coenzyme Q10

300 mg/day (150 mg/b.i.d)

OTHER

Placebo

Starch

Locations (1)

Chung Shan Medical University Hospital

Taichung, Taiwan